Objective To investigate the clinical effects of arthroscopic repair and reconstruction of anterior cruciate ligament repair (ACL) combined meniscus injury. Methods 40 cases of patients with anterior cruciate ligament (ACL) combined meniscus injury were selected, they were divided into experimental group (also repair ACL and meniscus), control group (meniscus repair), the Lysholm scores before and after surgery of the two groups, as well as the postoperative Lysholm scores of the two groups were observed. Then compared the meniscal healing rate after surgery and meniscal reoperation rate after 2 years of the two groups. Results The postoperative Lysholm score after surgery was higher than before surgery, but the Lysholm score of the experimental group was higher than that in control group. The healing rate of the experimental group was higher than that in control group, the meniscus reoperation rate after 2 years was lower than that in control group. Conclusion Arthroscopic repair and reconstruction of anterior cruciate ligament (ACL) and meniscus injury can improve the cure rate, is conducive to postoperative rehabilitation, and the long-term effect is obvious, so is worthy of promoting.