Abstract: Objective?To investigate the remedial effect of additional oral laxatives and clean enema on patients with inadequate bowel preparation for general colonoscopy.?Methods?The clinical data of 96 patients from July 2018 to June 2019 with inadequate bowel preparation [total Boston Bowel Preparation Scale (BBPS) score less than 6 or any of 3 colon segments score less than 2] during an general colonoscopy and received remedial measures on the same day were retrospectively analyzed. Among them, 59 patients received additional oral intake of 2 L polyethylene glycol (PEG) electrolyte powder (PEG group) and 37 patients received artificial clean enema (enema group). The BBPS score of colon, adequacy rate of bowel preparation, time of cecum intubation, detection rate of polyps, adverse reactions and patients’ acceptance were compared between the two groups.?Results?The BBPS score of whole colon [(7.9?±?1.8) vs (7.1?±?1.7) score, t?=?2.17, P?=?0.033], right colon [(2.7?±?0.8) vs (2.2?±?0.7) score, t?=?3.12, P?=?0.002] and transverse colon [(2.7?±?0.8) vs (2.3?±?0.7) score, t?=?2.50, P?=?0.014] in PEG group was significantly higher, adequacy rate of bowel preparation (93.2% vs 73.0%, χ2?=?7.48, P?=?0.006) was significantly higher, and patients’ acceptance (91.5% vs 75.7%, χ2?=?4.59, P?=?0.032) was significantly higher than those in enema group, with statistical significance (P?